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RR1 and RR2 gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

《农业科学与工程前沿（英文）》 2016年第3卷第1期页码 81-86 doi: 10.15302/J-FASE-2016088

摘要： As virulence-determining genes, and encode the small subunit and large subunit of viral ribonucleotide reductase (RR) in pseudorabies virus which have been extensively studied in mice. However, their role in pigs has not been adequately investigated. In this study, we deleted and genes based on a / / triple gene-deleted pseudorabies virus and tested its efficacy in pigs as a vaccine candidate. The rescued virus showed similar growth properties and plaque size as its parent strain. In an animal study, the virus could elicit humoral immune responses shown by generation of gB-specific antibodies and virus neutralizing antibodies. However, vaccination could not provide protection against virulent pseudorabies virus challenge since vaccinated pigs showed clinical pseudorabies-specific syndromes. The deficiency in protection may due to the generation of late and low levels of gB antibodies and virus neutralizing antibodies.

关键词： pseudorabies virus RR1 and RR2 ribonucleotide reductase vaccine candidate

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HAM：一种融入文本信息的深度协同排序方法 Research Articles

王铖微1,3,周腾飞3,谌晨1,3,胡天磊1,3,陈刚2,3

《信息与电子工程前沿（英文）》 2020年第21卷第8期页码 1119-1266 doi: 10.1631/FITEE.1900382

摘要：基于文本语料库的推荐任务旨在通过挖掘用户反馈数据以及物品文本描述数据对用户偏好建模。当前研究人员亟需探索使用深度神经网络捕获复杂的非线性偏好。然而，训练网络结构更深的推荐器并不能通过简单添加网络层数实现。一个网络结构更深的推荐器会面临梯度消失/爆炸问题，导致其无法通过基于梯度的方法进行模型训练。此外，物品文字描述数据可能包含嘈杂的单词序列；直接从这类特征向量中提取特征可能会影响推荐器性能。为解决上述问题，本文提出一种新的基于极深神经网络的排序推荐方法：高速网络推荐器(HighwAy recoMmender, HAM)。首先基于高速公路网络设计一个全新神经网络推荐框架，该框架能有效地稳定深度推荐器的梯度流。其次，使用一种多头注意力编码器，自动对文本信息降噪。最后，提出一种全新的基于块坐标下降的方法，可更加有效地训练具有更深网络结构的推荐器。实验结果表明，与当前先进方法相比，HAM具有更好推荐性能。

关键词：深度学习；推荐系统；高速公路网络；块坐标梯度下降

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Recent advances and challenges of nitrogen/nitrate electro catalytic reduction to ammonia synthesis

《能源前沿（英文）》 doi: 10.1007/s11708-023-0908-2

摘要： The Haber-Bosch process is the most widely used synthetic ammonia technology at present. Since its invention, it has provided an important guarantee for global food security. However, the traditional Haber-Bosch ammonia synthesis process consumes a lot of energy and causes serious environmental pollution. Under the serious pressure of energy and environment, a green, clean, and sustainable ammonia synthesis route is urgently needed. Electrochemical synthesis of ammonia is a green and mild new method for preparing ammonia, which can directly convert nitrogen or nitrate into ammonia using electricity driven by solar, wind, or water energy, without greenhouse gas and toxic gas emissions. Herein, the basic mechanism of the nitrogen reduction reaction (NRR) to ammonia and nitrate reduction reaction (

NO 3 −

RR) to ammonia were discussed. The representative approaches and major technologies, such as lithium mediated electrolysis and solid oxide electrolysis cell (SOEC) electrolysis for NRR, high activity catalyst and advanced electrochemical device fabrication for

NO 3 −

RR and electrochemical ammonia synthesis were summarized. Based on the above discussion and analysis, the main challenges and development directions for electrochemical ammonia synthesis were further proposed.

关键词： electrochemical ammonia synthesis nitrogen nitrate nitrogen reduction reaction (NRR) to ammonia nitrate reduction reaction (NO^–3 RR)

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Dynamic modeling of flexible-links planar parallel robots

DU Zhaocai, YU Yueqing, ZHANG Xuping, DU Zhaocai

《机械工程前沿（英文）》 2008年第3卷第2期页码 232-237 doi: 10.1007/s11465-008-0032-3

摘要： This paper presents a finite element-based method for dynamic modeling of parallel robots with flexible links and rigid moving platform. The elastic displacements of flexible links are investigated while considering the coupling effects between links due to the structural flexibility. The kinematic constraint conditions and dynamic constraint conditions for elastic displacements are presented. Considering the effects of distributed mass, lumped mass, shearing deformation, bending deformation, tensile deformation and lateral displacements, the Kineto-Elasto dynamics (KED) theory and Lagrange formula are used to derive the dynamic equations of planar flexible-links parallel robots. The dynamic behavior of the flexible-links planar parallel robot is well illustrated through numerical simulation of a planar 3-RR parallel robot. Compared with the results of finite element software SAMCEF, the numerical simulation results show good coherence of the proposed method. The flexibility of links is demonstrated to have a significant impact on the position error and orientation error of the flexible-links planar parallel robot.

关键词： 3-RR parallel KED coupling software SAMCEF orientation

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基于半导体纳米晶体的神经突触器件 Review

步明轩1,2,王越1,2,尹蕾1,2,童周禹1,2,张懿强3,杨德仁1,2,4,5,皮孝东1,2,4,5

《信息与电子工程前沿（英文）》 2022年第23卷第11期页码 1579-1601 doi: 10.1631/FITEE.2100551

摘要：

近年来，人们对信息处理的需求日益增长，脑启发式神经形态器件得到了广泛的关注。突触器件作为一类重要的神经形态器件，在短短几年内迅速升温。在用于制备突触器件的各种材料中，半导体纳米晶体（NCs）因其优异的电学和光学性能而成为首选材料之一。本综述论文首先介绍了基于半导体纳米晶体的突触器件的研究背景及半导体纳米晶体的基本性质。然后，根据器件有源层所用纳米晶体种类的不同，分类介绍了基于纳米晶体的突触器件的最新研究进展。最后，讨论了基于半导体纳米晶体的突触器件目前仍面临的问题和挑战。

关键词：半导体纳米晶体；突触器件；神经形态计算

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面向语义通信的模分多址技术 Research Article

张平1,2,3,许晓东1,2,3,董辰1,牛凯1,2,梁灏泰1,梁子键1,秦晓琦1,孙梦颖1,陈昊2,马楠1,2,许文俊1,王光宇1,陶小峰2,4

《信息与电子工程前沿（英文）》 2023年第24卷第6期页码 801-812 doi: 10.1631/FITEE.2300196

摘要：在多用户系统中，系统资源应分配给不同用户。在传统通信系统中，系统资源通常包括时间、频率、空间和功率，因此广泛使用诸如时分多址（TDMA）、频分多址（FDMA）、空分多址（SDMA）、码分多址（CDMA）、非正交多址（NOMA）之类多址技术。在被认为是下一代通信系统新范式的语义通信中，我们从语义角度，以基于模型的人工智能方法，从信源中提取高维语义域特征，并针对信源和信道特征联合构建模型信息空间。从模型信息空间中挖掘语义信息的共性化和个性化信息，提出一种新的基于语义域资源的多址技术，称为模分多址（MDMA）。从信息论角度，证明模分多址比传统多址技术获得更多性能提升。仿真结果表明，模分多址比传统多址技术节省更多带宽资源，并且在低信噪比条件下，在加性高斯白噪声（AWGN）信道中，相比非正交多址具有至少5 dB的性能优势。

关键词：模分多址（MDMA）；语义通信；多址技术

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基于玻璃通孔的Ka波段宽带滤波封装天线 Research Article

方针1,2,张继华1,2,3,高莉彬1,2,陈宏伟1,2,李文磊1,2,梁天鹏1,2,蔡旭东1,2,蔡星周3,贾惟聪3,郭欢3,李勇3

《信息与电子工程前沿（英文）》 2023年第24卷第6期页码 916-926 doi: 10.1631/FITEE.2200573

摘要： BPF单元有3对λg/4槽(缺陷微带结构)和两对λg/2 U形缝隙(缺陷地结构)。该天线实现了大带宽和高辐射效率，这可能与玻璃基板的叠加和玻璃通孔馈电有关。

关键词：滤波封装天线；玻璃通孔；三维封装器件；激光键合

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Microwave-assisted synthesis and antimicrobial activities of 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin

Hua CHEN, Yanan LI, Jie BAI, Lian ZHAO, Xiangguo YUAN, Xiaoliu LI, Keqiang CAO

《化学科学与工程前沿（英文）》 2009年第3卷第2期页码 186-191 doi: 10.1007/s11705-009-0004-0

摘要： 2-aryl-3-(naphthalene-1 or 2-yl)-1,3-thiazolidin-4-ones and were synthesized in 41%-67% yield by using microwave-assisted one-pot protocol. The structures of the new compounds , , , , , , and - were confirmed by IR, NMR, MS, and elemental analysis. The antimicrobial activities of the compounds against pv. lachrymans (Smith et Bryan) Young, Dye & Wilkie, Pers., and Blum. were examined. Some of the compounds showed good antifungical activity against Blum.

关键词： microwave-assisted synthesis naphthyl thiazolidin-4-one antimicrobial

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磁控溅射法生长的带隙可调谐(GaxIn1−x)2O3 Research Articles

张法碧1,孙巾寓1,李海鸥1,周娟1,王荣1,孙堂友1,傅涛1,肖功利1,李琦1,刘兴鹏1,张秀云1,郭道友2,王相虎3,秦祖军1

《信息与电子工程前沿（英文）》 2021年第22卷第10期页码 1370-1378 doi: 10.1631/FITEE.2000330

摘要：采用磁控溅射技术和热退火技术在(0001)蓝宝石衬底上制备了多组分氧化物(GaxIn1−x)2O3薄膜，实现可调带隙。详细研究了三元化合物(GaxIn1−x)2O3在整个组成范围内的光学性质和能带结构演化。X射线衍射谱表明，Ga含量在0.11至0.55之间的(GaxIn1−x)2O3薄膜既有立方结构，也有单斜结构，而Ga含量高于0.74的(GaxIn1−x)2O3薄膜只有单斜结构。实验结果为透明导电化合物半导体(GaxIn1−x)2O3薄膜在光电和光伏行业的应用，特别是在显示器、发光二极管和太阳能电池的应用奠定了基础。

关键词： (GaxIn1−x)2O3薄膜；带隙可调谐；磁控溅射

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一种基于业务需求与流量感知的卫星网络多路径路由算法 Research Article

邢紫阳1,2,祁晖1,2,底晓强1,2,3,刘晋尧1,2,许睿1,2,陈静1,2,从立钢1,2

《信息与电子工程前沿（英文）》 2023年第24卷第6期页码 844-858 doi: 10.1631/FITEE.2200507

摘要：随着低轨卫星制造和发射成本的降低，以及其覆盖范围大、数据传输速率高等优点，低轨卫星已成为空地网络数据传输的重要组成部分。但受地理位置及人们生活习惯等因素影响，用户对数据需求差异会造成网络流量不均衡，可能导致网络拥塞进而影响数据传输。传统卫星网络获取网络信息收敛慢，无法细粒度收集全局网络信息，不利于计算最优路由。多业务请求无法满足服务质量要求。本文将人工智能技术应用于低轨卫星网络，利用软件定义网络获取全局网络信息，感知网络流量，通过强化学习在线制定综合决策，实时更新最优路由策略。仿真结果表明，所提强化学习算法有良好收敛性和较强泛化能力。与传统路由相比，本文算法吞吐量提高了8%，且具有负载均衡性。

关键词：软件定义网络（SDN）；快速用户数据报协议互联网连接（QUIC）；强化学习；Sketch；多业务需求；卫星网络

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金属网栅透明导电膜光电性能综合评价因子 Research Articles

张怡蕾1,2,曹瑾璇1,2,陆振刚1,2,王赫岩1,2,谭久彬1,2

《信息与电子工程前沿（英文）》 2021年第22卷第11期页码 1532-1540 doi: 10.1631/FITEE.2000690

摘要：获取金属网栅最佳光电性能（零级光学透光率、电磁屏蔽效能和杂散光均匀性）对其在透明电磁屏蔽领域的应用具有重要价值。然而，目前相关研究较少。本文提出一种基于金属网栅光电性能的形式简单的综合评价因子Q，可简便有效地用于不同结构参数的金属网栅光电性能评估。评价因子Q值与TOPSIS的评估结果变化趋势一致，验证了评价因子Q的有效性。评价因子Q还可以对不同图案的金属网栅光电性能进行评估，使其在金属网栅的设计和应用中具有十分广泛的应用前景。

关键词：金属网栅；TOPSIS法；熵权法；综合评价因子；透明导电膜

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流体内磁驱动微米机器人运动前沿研究综述 Review Article

苗佳淼1,2,王潇朴2,周燕2,叶敏2,赵洪宇2,许若愚1,钱辉环1,2

《信息与电子工程前沿（英文）》 2023年第24卷第11期页码 1520-1540 doi: 10.1631/FITEE.2300054

摘要：磁驱动微米机器人能够在人体内局部低侵入性地执行特定任务。为到达体内病灶区域，微米机器人常常需要在比静止液体更为复杂的流动血液内进行导航运动。因此，相应的精准控制方案设计更具挑战性。目前已有许多关于磁控微米机器人在流体内的运动控制及其理论研究。本文回顾总结了有关磁控微米机器人在流体中的最新研究进展，包括流动系统的建立、运动的动力学建模以及控制方法。此外，讨论了当前面临的挑战和局限性。希望本文为微米机器人在复杂流体环境中的高效控制提供新的思路，并加快微米机器人在临床应用中的研究。

关键词：微米机器人；流体；动力学建模；控制

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Multistep conversion of cresols by phenol hydroxylase and 2,3-dihydroxy-biphenyl 1,2-dioxygenase

Shengnan SHI,Fang MA,Tieheng SUN,Ang LI,Jiti ZHOU,Yuanyuan QU

《环境科学与工程前沿（英文）》 2014年第8卷第4期页码 539-546 doi: 10.1007/s11783-013-0616-y

摘要： A multistep conversion system composed of phenol hydroxylase (PH ) and 2,3-dihydroxy-biphenyl 1,2-dioxygenase (BphC ) was used to synthesize methylcatechols and semialdehydes from - and -cresol for the first time. Docking studies displayed by PyMOL predicted that cresols and methylcatechols could be theoretically transformed by this multistep conversion system. High performance liquid chromatography mass spectrometry (HPLC-MS) analysis also indicated that the products formed from multistep conversion were the corresponding 3-methylcatechol, 4-methylcatechol, 2-hydroxy-3-methyl-6-oxohexa-2,4-dienoic acid (2-hydroxy-3-methyl-ODA) and 2-hydroxy-5-methyl-6-oxohexa-2,4-dienoic acid (2-hydroxy-5-methyl-ODA). The optimal cell concentrations of the recombinant strain BL21 (DE3) expressing phenol hydroxylase (PH ) and 2,3-dihydroxy-biphenyl 1,2-dioxygenase (BphC ) and pH for the multistep conversion of - and -cresol were 4.0 (g·L cell dry weight) and pH 8.0, respectively. For the first step conversion, the formation rate of 3-methylcatechol (0.29 μmol·L ·min ·mg cell dry weight) from -cresol was similarly with that of methylcatechols (0.28 μmol·L ·min ·mg cell dry weight) from -cresol by strain PH . For the second step conversion, strain BphC showed higher formation rate (0.83 μmol·L ·min ·mg cell dry weight) for 2-hydroxy-3-methyl-ODA and 2-hydroxy-5-methyl-ODA from -cresol, which was 1.1-fold higher than that for 2-hydroxy-3-methyl-ODA (0.77 μmol·L ·min ·mg cell dry weight) from -cresol. The present study suggested the potential application of the multistep conversion system for the production of chemical synthons and high-value products.

关键词： multistep conversion cresols phenol hydroxylase 2 3-dihydroxybiphenyl 1 2-dioxygenase methylcatechols

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Encapsulation of 2-amino-2-methyl-1-propanol with tetraethyl orthosilicate for CO2 capture

Sidra Rama, Yan Zhang, Fideline Tchuenbou-Magaia, Yulong Ding, Yongliang Li

《化学科学与工程前沿（英文）》 2019年第13卷第4期页码 672-683 doi: 10.1007/s11705-019-1856-6

摘要： Carbon capture is widely recognised as an essential strategy to meet global goals for climate protection. Although various CO capture technologies including absorption, adsorption and membrane exist, they are not yet mature for post-combustion power plants mainly due to high energy penalty. Hence researchers are concentrating on developing non-aqueous solvents like ionic liquids, CO -binding organic liquids, nanoparticle hybrid materials and microencapsulated sorbents to minimize the energy consumption for carbon capture. This research aims to develop a novel and efficient approach by encapsulating sorbents to capture CO in a cold environment. The conventional emulsion technique was selected for the microcapsule formulation by using 2-amino-2-methyl-1-propanol (AMP) as the core sorbent and silicon dioxide as the shell. This paper reports the findings on the formulated microcapsules including key formulation parameters, microstructure, size distribution and thermal cycling stability. Furthermore, the effects of microcapsule quality and absorption temperature on the CO loading capacity of the microcapsules were investigated using a self-developed pressure decay method. The preliminary results have shown that the AMP microcapsules are promising to replace conventional sorbents.

关键词： carbon capture microencapsulated sorbents emulsion technique low temperature adsorption and absorption

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基于孔径耦合微带结构馈电的单脉冲透射阵天线 Correspondence

寇娜1,2,3,余世星1,2,3,丁召1,2,3,张正平1,2,3

《信息与电子工程前沿（英文）》 2022年第23卷第3期页码 502-510 doi: 10.1631/FITEE.2000547

摘要：设计、加工、并测试了一款X波段单脉冲透射阵天线，该天线由平面透射阵和馈源天线组成，其中馈源天线集成了基于孔径耦合的微带结构以及和差网络。仿真和测试结果表明，所提单脉冲天线具有21.5 dBi主波束增益，副瓣电平值在−13.4 dB以下，交叉极化电平值小于−20 dB。此外，和波束与差波束在E面和H面的增益比值分别为5.6 dB和4 dB。该天线具有重量轻、成本低等优点，有望用于低成本动中通系统。

关键词：孔径耦合；单脉冲天线；微带；透射阵列

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标题作者时间类型操作

RR1 and RR2 gene deletion affects the immunogenicity of a live attenuated pseudorabies

Shijun YAN,He YAN,Chaolin ZHANG,Tongyan WANG,Qingyuan YANG,Zhe SUN,Yan XIAO,Feifei TAN,Xiangdong LI,Kegong TIAN

期刊论文

HAM：一种融入文本信息的深度协同排序方法

王铖微1,3,周腾飞3,谌晨1,3,胡天磊1,3,陈刚2,3

期刊论文

Recent advances and challenges of nitrogen/nitrate electro catalytic reduction to ammonia synthesis

期刊论文

Dynamic modeling of flexible-links planar parallel robots